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European Journal of Cancer

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Articles
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  Original Research
  Open Access
  Long-term survival with IDH wildtype glioblastoma: first results from the ETERNITY Brain Tumor Funders’ Collaborative Consortium (EORTC 1419)
  Hertler et al.
  Original Research
  Open Access
  Phase 2 study of osimertinib in combination with platinum and pemetrexed in patients with previously untreated EGFR-mutated advanced non-squamous non-small cell lung cancer: The OPAL Study
  Saito et al.
  Original Research
  Open Access
  Intra-patient and inter-metastasis heterogeneity of HER2-low status in metastatic breast cancer
  Geukens et al.
- Latest Articles
  Letter to the Editor
  Cancer in conflict: The impact of the war in Ukraine on Moldova
  Horia Vulpe
  Artiom Minzatean
  Stefania Magidson
  Irena Tocino
  Rodica Mindruta-Stratan
  Lars Johan Lönnback
  Ursula Wagner
  Violina Nazaria
  Eugenia Ciubotaru
  Nicoleta Minzatean
  Veronica Ciobanu
  Sergiu Brenister
  Ludmila Circiumari
  Cristian Teglas
  Richard Sullivan
  Ruslan Baltaga
  Current Perspective
  The emerging promise of tumor mechanobiology in cancer treatment
  Papavassiliou et al.
  Letter to the Editor
  Long-lasting CRs after ibrutinib monotherapy for relapse or refractory primary CNS lymphoma (PCNSL) and primary vitreoretinal lymphoma (PVRL): Long-term results of the iLOC study by the Lymphoma Study Association (LYSA) and the French Oculo-Cerebral Lymphoma (LOC) Network (clinical trial number: NCT02542514)
  Carole Soussain
  Denis Malaise
  Sylvain Choquet
  Hervé Ghesquières
  Caroline Houillier
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Issue cover

January 2019

Volume 106p1-244

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Editorial

Induction chemotherapy in borderline (non-)resectable pancreatic cancer: a unique window of opportunity for understanding pancreatic cancer

Jean-Luc Van Laethem

Published online: November 19, 2018

p34-36

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Breast cancer

European Breast Cancer Council manifesto 2018: Genetic risk prediction testing in breast cancer

Emiel Rutgers,
Judith Balmana,
Marc Beishon,
...
Dominique Stoppa-Lyonnet,
Luzia Travado,
Lynda Wyld

Published online: November 21, 2018

p45-53

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Genetic counselling and testing of susceptibility genes for therapeutic decision-making in breast cancer—an European consensus statement and expert recommendations

Christian F. Singer,
Judith Balmaña,
Nicole Bürki,
...
Kerstin Rhiem,
Manuel Teixeira,
D. Gareth Evans

Published online: November 21, 2018

p54-60

Open Access

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Association of clinical outcomes in metastatic breast cancer patients with circulating tumour cell and circulating cell-free DNA

Association of clinical outcomes in metastatic breast cancer patients with circulating tumour cell and circulating cell-free DNA

Zhong Ye,
Chun Wang,
Shaogui Wan,
...
Bingshan Li,
Massimo Cristofanilli,
Hushan Yang

Published online: December 04, 2018

p133-143

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Intense dose-dense epirubicin, paclitaxel, cyclophosphamide versus weekly paclitaxel, liposomal doxorubicin (plus carboplatin in triple-negative breast cancer) for neoadjuvant treatment of high-risk early breast cancer (GeparOcto—GBG 84): A randomised phase III trial

Intense dose-dense epirubicin, paclitaxel, cyclophosphamide versus weekly paclitaxel, liposomal doxorubicin (plus carboplatin in triple-negative breast cancer) for neoadjuvant treatment of high-risk early breast cancer (GeparOcto—GBG 84): A randomised phase III trial

Andreas Schneeweiss,
Volker Möbus,
Hans Tesch,
...
Valentina Nekljudova,
Gunter von Minckwitz,
Sibylle Loibl

Published online: December 04, 2018

p181-192

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Lung cancer

Predictive biomarkers of response for immune checkpoint inhibitors in non–small-cell lung cancer

Arsela Prelaj,
Rebecca Tay,
Roberto Ferrara,
Nathalie Chaput,
Benjamin Besse,
Raffaele Califano

Published online: December 04, 2018

p144-159

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Gastrointestinal oncology

Quality of life in metastatic pancreatic cancer patients receiving liposomal irinotecan plus 5-fluorouracil and leucovorin

Quality of life in metastatic pancreatic cancer patients receiving liposomal irinotecan plus 5-fluorouracil and leucovorin

Richard A. Hubner,
Antonio Cubillo,
Jean-Frédéric Blanc,
...
Yoojung Yang,
Floris A. de Jong,
Jens T. Siveke

Published online: November 17, 2018

p24-33

Open Access

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Efficacy of bevacizumab in first-line treatment of metastatic colorectal cancer: A systematic review and meta-analysis

Efficacy of bevacizumab in first-line treatment of metastatic colorectal cancer: A systematic review and meta-analysis

Alexander Baraniskin,
Barbara Buchberger,
Christian Pox,
...
Julian W. Holch,
Wolff Schmiegel,
Volker Heinemann

Published online: November 22, 2018

p37-44

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Efficacy of adjuvant chemotherapy after resection of pulmonary metastasis from colorectal cancer: a propensity score–matched analysis

Efficacy of adjuvant chemotherapy after resection of pulmonary metastasis from colorectal cancer: a propensity score–matched analysis

Mamiko Imanishi,
Yoshiyuki Yamamoto,
Yukako Hamano,
...
Narikazu Boku,
Haruhiko Kondo,
Ichinosuke Hyodo

Published online: November 22, 2018

p69-77

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$TAS-118 (S-1 plus leucovorin) versus S-1 in patients with gemcitabine-refractory advanced pancreatic cancer: a randomised, open-label, phase 3 study (GRAPE trial)$

TAS-118 (S-1 plus leucovorin) versus S-1 in patients with gemcitabine-refractory advanced pancreatic cancer: a randomised, open-label, phase 3 study (GRAPE trial)

Tatsuya Ioka,
Makoto Ueno,
Hideki Ueno,
...
Takuji Okusaka,
Narikazu Boku,
Ichinosuke Hyodo

Published online: November 22, 2018

p78-88

Open Access

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Association between primary origin (head, body and tail) of metastasised pancreatic ductal adenocarcinoma and oncologic outcome: A population-based analysis

Association between primary origin (head, body and tail) of metastasised pancreatic ductal adenocarcinoma and oncologic outcome: A population-based analysis

Tara M. Mackay,
Felice N. van Erning,
Lydia G.M. van der Geest,
...
Marc G. Besselink,
Johanna W. Wilmink
for the Dutch Pancreatic Cancer Group

Published online: November 23, 2018

p99-105

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Relevance of baseline carcinoembryonic antigen for first-line treatment against metastatic colorectal cancer with FOLFIRI plus cetuximab or bevacizumab (FIRE-3 trial)

Relevance of baseline carcinoembryonic antigen for first-line treatment against metastatic colorectal cancer with FOLFIRI plus cetuximab or bevacizumab (FIRE-3 trial)

J.W. Holch,
I. Ricard,
S. Stintzing,
...
J.C. von Einem,
M. Michl,
V. Heinemann

Published online: November 27, 2018

p115-125

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Membrane human equilibrative nucleoside transporter 1 is associated with a high proliferation rate and worse survival in resected intrahepatic cholangiocarcinoma patients not receiving adjuvant treatments

Membrane human equilibrative nucleoside transporter 1 is associated with a high proliferation rate and worse survival in resected intrahepatic cholangiocarcinoma patients not receiving adjuvant treatments

S. Tavolari,
M. Deserti,
F. Vasuri,
...
A. D'Errico-Grigioni,
M.A. Pantaleo,
G. Brandi

Published online: December 04, 2018

p160-170

Open Access

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Urologic oncology

Performance of the Food and Drug Administration/EMA-approved programmed cell death ligand-1 assays in urothelial carcinoma with emphasis on therapy stratification for first-line use of atezolizumab and pembrolizumab

Performance of the Food and Drug Administration/EMA-approved programmed cell death ligand-1 assays in urothelial carcinoma with emphasis on therapy stratification for first-line use of atezolizumab and pembrolizumab

Markus Eckstein,
Philipp Erben,
Maximilian C. Kriegmair,
...
Christian Bolenz,
Arndt Hartmann,
Franziska Erlmeier

Published online: December 05, 2018

p234-243

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Head and neck oncology

$Impact of dose interruption on the efficacy of lenvatinib in a phase 3 study in patients with radioiodine-refractory differentiated thyroid cancer$

Impact of dose interruption on the efficacy of lenvatinib in a phase 3 study in patients with radioiodine-refractory differentiated thyroid cancer

Makoto Tahara,
Marcia S. Brose,
Lori J. Wirth,
...
Katsuki Fujino,
Corina E. Dutcus,
Andrew Gianoukakis

Published online: November 21, 2018

p61-68

Open Access

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Sarcoma

Activity of axitinib in progressive advanced solitary fibrous tumour: Results from an exploratory, investigator-driven phase 2 clinical study

Activity of axitinib in progressive advanced solitary fibrous tumour: Results from an exploratory, investigator-driven phase 2 clinical study

S. Stacchiotti,
N. Simeone,
S. Lo Vullo,
...
A.M. Frezza,
L. Mariani,
P.G. Casali

Published online: December 05, 2018

p225-233

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Hematology

All-oral ixazomib, cyclophosphamide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma

All-oral ixazomib, cyclophosphamide, and dexamethasone for transplant-ineligible patients with newly diagnosed multiple myeloma

Meletios A. Dimopoulos,
Sebastian Grosicki,
Wiesław W. Jędrzejczak,
...
Huyuan Yang,
Norbert Grzasko,
Shaji Kumar

Published online: November 22, 2018

p89-98

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Impact of anti-thymocyte globulin on results of allogeneic peripheral blood stem cell transplantation for patients with Philadelphia-positive acute lymphoblastic leukaemia: An analysis by the Acute Leukemia Working Party of the EBMT

Impact of anti-thymocyte globulin on results of allogeneic peripheral blood stem cell transplantation for patients with Philadelphia-positive acute lymphoblastic leukaemia: An analysis by the Acute Leukemia Working Party of the EBMT

Sebastian Giebel,
Myriam Labopin,
Tomasz Czerw,
...
Martin Bornhäuser,
Mohamad Mohty,
Arnon Nagler

Published online: December 05, 2018

p212-219

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Pediatric oncology

Microscopically positive resection margin after hepatoblastoma resection: what is the impact on prognosis? A Childhood Liver Tumours Strategy Group (SIOPEL) report

Microscopically positive resection margin after hepatoblastoma resection: what is the impact on prognosis? A Childhood Liver Tumours Strategy Group (SIOPEL) report

Daniel C. Aronson,
Víola B. Weeda,
Rudolf Maibach,
...
Bruce Morland,
Laurence Brugières
for the Childhood Liver Tumour Strategy Group (SIOPEL)

Published online: December 05, 2018

p126-132

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Long-term health and social function in adult survivors of paediatric astrocytoma: A report from the Childhood Cancer Survivor Study

Long-term health and social function in adult survivors of paediatric astrocytoma: A report from the Childhood Cancer Survivor Study

Karen E. Effinger,
Kayla L. Stratton,
Paul Graham Fisher,
...
Melissa M. Hudson,
Wendy M. Leisenring,
Paul C. Nathan

Published online: December 04, 2018

p171-180

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Basic science and preclinical research

Evaluation of objective response, disease control and progression-free survival as surrogate end-points for overall survival in anti–programmed death-1 and anti–programmed death ligand 1 trials

Evaluation of objective response, disease control and progression-free survival as surrogate end-points for overall survival in anti–programmed death-1 and anti–programmed death ligand 1 trials

Run-Cong Nie,
Fo-Ping Chen,
Shu-Qiang Yuan,
...
Ying-Bo Chen,
Yuan-Fang Li,
Zhi-Wei Zhou

Published online: November 16, 2018

p1-11

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Tumour Immunology and Immunotherapy

Myositis and neuromuscular side-effects induced by immune checkpoint inhibitors

Myositis and neuromuscular side-effects induced by immune checkpoint inhibitors

Alvaro Moreira,
Carmen Loquai,
Claudia Pföhler,
...
Lisa Zimmer,
Rolf Schröder,
Lucie Heinzerling

Published online: November 17, 2018

p12-23

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Evolution and recurrence of gastrointestinal immune-related adverse events induced by immune checkpoint inhibitors

Evolution and recurrence of gastrointestinal immune-related adverse events induced by immune checkpoint inhibitors

Alice de Malet,
Guillemette Antoni,
Michael Collins,
...
Christine Mateus,
Caroline Robert,
Franck Carbonnel

Published online: November 23, 2018

p106-114

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Other

A systematic review of trial-level meta-analyses measuring the strength of association between surrogate end-points and overall survival in oncology

A systematic review of trial-level meta-analyses measuring the strength of association between surrogate end-points and overall survival in oncology

Alyson Haslam,
Spencer P. Hey,
Jennifer Gill,
Vinay Prasad

Published online: December 05, 2018

p196-211

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Correspondence

Presence of antibodies to striated muscle and acetylcholine receptor in association with occurrence of myasthenia gravis with myositis and myocarditis in a patient with melanoma treated with an anti–programmed death 1 antibody

Presence of antibodies to striated muscle and acetylcholine receptor in association with occurrence of myasthenia gravis with myositis and myocarditis in a patient with melanoma treated with an anti–programmed death 1 antibody

T. Shirai,
Y. Kiniwa,
R. Sato,
...
N. Ohashi,
Y. Sekijima,
R. Okuyama

Published online: December 05, 2018

p193-195

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Diet-dependent toxicity of ipilimumab in metastatic melanoma

Diet-dependent toxicity of ipilimumab in metastatic melanoma

P. Majenka,
M. Hoffmann,
I. Rötzer,
...
T. Longerich,
A. Enk,
J.C. Hassel

Published online: December 05, 2018

p220-224

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Reviewer acknowledgment

Reviewers 2018

Published in issue: January 2019

p244

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