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May 2013

Volume 49Issue 8p1799-2076

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Drug development

A dose finding, safety and pharmacokinetic study of AVE1642, an anti-insulin-like growth factor-1 receptor (IGF-1R/CD221) monoclonal antibody, administered as a single agent and in combination with docetaxel in patients with advanced solid tumours

Jean Charles Soria,
Christophe Massard,
Vladimir Lazar,
...
Dominique Mery-Mignard,
Antoine Deslandes,
Anthony W. Tolcher

Published online: March 01, 2013

p1799-1807

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Design and conduct of early clinical studies of two or more targeted anticancer therapies: Recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies

Lesley K. Seymour,
A. Hilary Calvert,
Marinus W. Lobbezoo,
Elizabeth A. Eisenhauer,
Giuseppe Giaccone

Published online: February 20, 2013

p1808-1814

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Phase I–IIa study of BMS-690514, an EGFR, HER-2 and -4 and VEGFR-1 to -3 oral tyrosine kinase inhibitor, in patients with advanced or metastatic solid tumours

Jean-Charles Soria,
José Baselga,
Nasser Hanna,
...
John F. Kurland,
Ashutosh K. Pathak,
Roy S. Herbst

Published online: March 14, 2013

p1815-1824

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Breast cancer

Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients

N. Harbeck,
M. Schmitt,
C. Meisner,
...
M. Kiechle,
F. Jänicke,
C. Thomssen

Published online: March 14, 2013

p1825-1835

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Discharge of breast cancer patients to primary care at the end of hospital follow-up: A cross-sectional survey

Carriene Roorda,
Annette J. Berendsen,
Manon Haverkamp,
Klaas van der Meer,
Geertruida H. de Bock

Published online: March 01, 2013

p1836-1844

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Exosomes from triple-negative breast cancer cells can transfer phenotypic traits representing their cells of origin to secondary cells

Keith O’Brien,
Sweta Rani,
Claire Corcoran,
...
John Crown,
Marek W. Radomski,
Lorraine O’Driscoll

Published online: March 01, 2013

p1845-1859

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Lung cancer

Combined endobronchial and endoscopic ultrasound-guided fine needle aspiration for mediastinal lymph node staging of lung cancer: A meta-analysis

Ruifeng Zhang,
Kejing Ying,
Liuhong Shi,
Lianfeng Zhang,
Lin Zhou

Published online: March 07, 2013

p1860-1867

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Gastrointestinal oncology

A randomised phase III intergroup trial comparing high-dose infusional 5-fluorouracil with or without folinic acid with standard bolus 5-fluorouracil/folinic acid in the adjuvant treatment of stage III colon cancer: The Pan-European Trial in Adjuvant Colon Cancer 2 study

Claus-Henning Köhne,
Laurent Bedenne,
Alfredo Carrato,
...
Jacques Wils,
Francesco Pignatti,
Frank Biertz

Published online: April 08, 2013

p1868-1875

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Amplification but not translocation of anaplastic lymphoma kinase is a frequent event in oesophageal cancer

Sebastian F. Schoppmann,
Berthold Streubel,
Peter Birner

Published online: March 14, 2013

p1876-1881

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Taking into account successive treatment lines in the analysis of a colorectal cancer randomised trial

J. Pénichoux,
S. Michiels,
O. Bouché,
...
P. Rougier,
M. Ducreux,
J.-P. Pignon

Published online: March 14, 2013

p1882-1888

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Urologic oncology

Impact of histological variants on oncological outcomes of patients with urothelial carcinoma of the bladder treated with radical cystectomy

Evanguelos Xylinas,
Michael Rink,
Brian D. Robinson,
...
Marc Zerbib,
Douglas S. Scherr,
Shahrokh F. Shariat

Published online: March 06, 2013

p1889-1897

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Second line treatment of metastatic renal cell carcinoma: The Institut Gustave Roussy experience with targeted therapies in 251 consecutive patients

Antonin Levy,
Jean Menard,
Laurence Albiges,
...
Mario Di Palma,
Karim Fizazi,
Bernard Escudier

Published online: March 14, 2013

p1898-1904

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Gynecologic oncology

Borderline tumours of the ovary: A cohort study of the Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) Study Group

Andreas du Bois,
Nina Ewald-Riegler,
Nikolaus de Gregorio,
...
Barbara Richter,
Stefan Kommoss,
Steffen Hauptmann

Published online: March 14, 2013

p1905-1914

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Head and neck cancer

High sex determining region Y-box 2 expression is a negative predictor of occult lymph node metastasis in early squamous cell carcinomas of the oral cavity

L. Züllig,
M. Roessle,
C. Weber,
...
S.J. Stoeckli,
H. Moch,
G.F. Huber

Published online: February 14, 2013

p1915-1922

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Pretreatment body mass index as an independent prognostic factor in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy: Findings from a randomised trial

Pei-Yu Huang,
Cheng-Tao Wang,
Ka-Jia Cao,
...
Yi-Shan Wu,
Hai-Qiang Mai,
Ming-Huang Hong

Published online: February 25, 2013

p1923-1931

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Sarcoma

Ovarian tissue cryopreserved for fertility preservation from patients with Ewing or other sarcomas appear to have no tumour cell contamination

Tine Greve,
Vera Timmermans Wielenga,
Morten Grauslund,
...
Dorte Bang Christiansen,
Mikkel Rosendahl,
Claus Yding Andersen

Published online: March 01, 2013

p1932-1938

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Pediatric oncology

Second cranio-facial malignancies in hereditary retinoblastoma survivors previously treated with radiation therapy: Clinic and radiologic characteristics and survival outcomes

Firazia Rodjan,
Pim de Graaf,
Hervé J. Brisse,
...
Dirk L. Knol,
Annette C. Moll,
Jonas A. Castelijns

Published online: February 18, 2013

p1939-1947

Open Access

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Quality of life

Inferior health-related quality of life and psychological well-being in immigrant cancer survivors: A population-based study

Phyllis N. Butow,
Lynley Aldridge,
Melanie L. Bell,
...
Priya Duggal-Beri,
Joshua McGrane,
David Goldstein

Published online: February 27, 2013

p1948-1956

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Quantifying fatigue in (long-term) colorectal cancer survivors: A study from the population-based Patient Reported Outcomes Following Initial treatment and Long term Evaluation of Survivorship registry

Melissa S.Y. Thong,
Floortje Mols,
Xin S. Wang,
Valery E.P.P. Lemmens,
Tineke J. Smilde,
Lonneke V. van de Poll-Franse

Published online: March 04, 2013

p1957-1966

Open Access

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End of life care

Awareness of General Practitioners concerning cancer patients’ preferences for place of death: Evidence from four European countries

Winne Ko,
Monica Beccaro,
Guido Miccinesi,
...
Massimo Costantini,
Lieve Van den Block
EURO IMPACT

Published online: February 18, 2013

p1967-1974

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Epidemiology

Incidence and survival of neuroendocrine tumours in the Netherlands according to histological grade: Experience of two decades of cancer registry

Catharina M. Korse,
Babs G. Taal,
Marie-Louise F. van Velthuysen,
Otto Visser

Published online: January 25, 2013

p1975-1983

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Differences in survival from prostate cancer in Denmark, Iceland and Sweden

Klaus Brasso,
Inga Jóna Ingimarsdóttir,
Ea Rusch,
...
Anna Bill-Axelson,
Erik Holmberg,
Hans Henrik Storm

Published online: March 04, 2013

p1984-1992

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Excess breast cancer risk in first degree relatives of CHEK2∗1100delC positive familial breast cancer cases

Muriel A. Adank,
Senno Verhoef,
Rogier A. Oldenburg,
...
Birgit I. Witte,
Marianne A. Jonker,
Hanne Meijers-Heijboer

Published online: February 18, 2013

p1993-1999

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Translational research

Cancer gene expression signatures – The rise and fall?

Frederic Chibon

Published online: March 15, 2013

p2000-2009

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Basic and preclinical research

miR-17-5p/20a are important markers for gastric cancer and murine double minute 2 participates in their functional regulation

Mei Wang,
Hongbing Gu,
Hui Qian,
...
Yang Tao,
Ling Zhang,
Wenrong Xu

Published online: January 18, 2013

p2010-2021

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A novel human anti-syndecan-1 antibody inhibits vascular maturation and tumour growth in melanoma

Paola Orecchia,
Romana Conte,
Enrica Balza,
...
PierLuigi Mauri,
Maria Cristina Mingari,
Barbara Carnemolla

Published online: January 28, 2013

p2022-2033

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Hepatitis A virus cellular receptor 1/kidney injury molecule-1 is a susceptibility gene for clear cell renal cell carcinoma and hepatitis A virus cellular receptor/kidney injury molecule-1 ectodomain shedding a predictive biomarker of tumour progression

Thaïs Cuadros,
Enric Trilla,
Maria Rosa Vilà,
...
Emilio Itarte,
Juan Morote,
Anna Meseguer

Published online: January 25, 2013

p2034-2047

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T-cadherin loss promotes experimental metastasis of squamous cell carcinoma

Maria Philippova,
Dennis Pfaff,
Emmanouil Kyriakakis,
...
Andreas W. Schoenenberger,
Paul Erne,
Therese J. Resink

Published online: January 31, 2013

p2048-2058

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Sildenafil is not a useful modulator of ABCB1 and ABCG2 mediated drug resistance in vivo

Fan Lin,
Lisette Hoogendijk,
Levi Buil,
Jos H. Beijnen,
Olaf van Tellingen

Published online: February 19, 2013

p2059-2064

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Correspondence

Modulation of intracellular pathways by anandamide and its evolving role in oncology

Shailendra Kapoor

Published online: February 25, 2013

p2065

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Anandamide inhibits the Wnt/β-catenin signalling pathway in human breast cancer MDA MB 231 cells

Chiara Laezza,
Alba d’Alessandro,
Anna Maria Malfitano,
Maurizio Bifulco

Published online: February 25, 2013

p2066-2067

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An updated meta-analysis about the association of Asp299Gly in Toll-like receptor 4 gene with risk of cancer

Xinxin Zhao,
Lingling Liu,
Shan Kang,
Dongfeng Zhang

Published online: February 27, 2013

p2068-2070

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Response to letter ‘An updated meta-analysis about the association of Asp299Gly in Toll-like receptor 4 gene with risk of cancer’

Kui Zhang,
Bin Zhou,
Yanyun Wang,
Li Rao,
Lin Zhang

Published online: March 07, 2013

p2071-2072

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Sun exposure, vitamin D and cancer risk reduction

William B. Grant

Published online: March 14, 2013

p2073-2075

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Popular Articles

May 2013

Drug development

Breast cancer

Lung cancer

Gastrointestinal oncology

Urologic oncology

Gynecologic oncology

Head and neck cancer

Sarcoma

Pediatric oncology

Quality of life

End of life care

Epidemiology

Translational research

Basic and preclinical research

Correspondence