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A multimodal approach for the management of co-morbid cardiotoxicity in the elderly breast cancer patients

      Background: Evidence-based best practices for risk stratification of elderly breast cancer patients are still lacking. Data for this patient population are scarce since elderly patients are underrepresented in clinical oncology trials. As a result, lower doses of chemotherapy are prescribed due to concerns for cardiotoxicity, frailty and high prevalence of multimorbidity [
      • Baris
      • et al.
      Management of Cardiovascular Disease in Women With Breast Cancer.
      ]. This contributes to undertreatment and suboptimal outcomes with a negative impact on the patients’ Quality of Life (QoL) [
      • Reddy P
      • et al.
      Cardio-oncology in the older adult.
      ]. CARDIOCARE project [ ] develops a novel and cost-effective risk stratification and healthcare model providing evidence-based best practices and care pathways to improve the management of multimorbid breast cancer patients at risk for cardiac toxicity.
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      References

        • Baris
        • et al.
        Management of Cardiovascular Disease in Women With Breast Cancer.
        Circulation. 2019; 139: 1110-1120
        • Reddy P
        • et al.
        Cardio-oncology in the older adult.
        J Geriatr Oncol. 2017; 8: 308-314
      1. Cardiocare project, https://cordis.europa.eu/project/id/945175