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Letter to the Editor| Volume 138, P189-192, October 2020

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Favorable outcome of HIV-associated Burkitt lymphoma in the modern combined antiretroviral therapy era

Published:September 05, 2020DOI:https://doi.org/10.1016/j.ejca.2020.07.033
      HIV infection is associated with a high risk of non-Hodgkin lymphoma (NHL), especially Burkitt's lymphoma (BL), which represents 10%–35% of HIV-associated NHL. The incidence of NHL has tended to decrease in the combined antiretroviral therapy (cART) era. This is not true for BL, for which the incidence appears to have been stable. Patients with BL present peculiar characteristics with higher CD4 counts, higher viral load and more recent HIV infection than other NHLs [
      • Hernández-Ramírez R.U.
      • Qin L.
      • Lin H.
      • Leyden W.
      • Neugebauer R.S.
      • Althoff K.N.
      • et al.
      Association of immunosuppression and HIV viraemia with non-Hodgkin lymphoma risk overall and by subtype in people living with HIV in Canada and the USA: a multicentre cohort study.
      ].
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