Highlights
- •All head and neck mucosa melanomas are classified as stage III-IV.
- •Prognosis is driven by distant metastases.
- •There is a role of ICI or targeted therapies as adjuvant treatment.
- •Adjuvant RT should be only offered in highly selected patients.
- •Consider entry to clinical trials to all patients.
Abstract
The United Kingdom head and neck mucosal melanoma guideline development group used
an evidence-based systematic approach to make recommendations in key areas of uncertainty
in the field, including accurate diagnosis and staging; the appropriate treatment
pathway including surgery, adjuvant radiation and new systemic treatments, such as
targeted agents and immunotherapy; and the surveillance of patients after treatment.
The guidelines were sent for international peer review and have been accredited by
the National Institute for Health and Care Excellence. A summary of key recommendations
is presented. The full documents are available on the Melanoma Focus website (https://melanomafocus.com/activities/mucosal-guidelines/mucosal-melanoma-resources/).
Keywords
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Article info
Publication history
Published online: August 20, 2020
Accepted:
July 19,
2020
Received in revised form:
July 3,
2020
Received:
May 25,
2020
Identification
Copyright
© 2020 Elsevier Ltd. All rights reserved.
