The article by Newton et al [
[1]
], advances the conversation on the role of chemotherapy in ovarian immature teratoma
(IT) and is very well written. The authors reviewed 42 patients with ovarian IT, 33
of whom had surgery alone and 9 patients had surgery and chemotherapy. They found
that recurrence risk was not reduced by first-line chemotherapy. This is similar to
our experience [
[2]
] and the experience of others [
[3]
].To read this article in full you will need to make a payment
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References
- A multicentre retrospective cohort study of ovarian germ cell tumours: evidence for chemotherapy de-escalation and alignment of paediatric and adult practice.Eur J Canc. 2019 May; 113: 19-27https://doi.org/10.1016/j.ejca.2019.03.001
- Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative.Cancer. 2016 Jan 15; 122: 230-237
- Is adjuvant chemotherapy indicated in stage I pure immature ovarian teratoma (IT)? A multicentre Italian trial in ovarian cancer (MITO-9).Gynecol Oncol. 2010; 119: 48-52
- Surgical resection alone is effective treatment for ovarian immature teratoma in children and adolescents: a report of the pediatric oncology group and the children's cancer group.Am J Obstet Gynecol. 1999; 181: 353-358
Article info
Publication history
Published online: March 13, 2020
Accepted:
January 12,
2020
Received:
November 23,
2019
Identification
Copyright
© 2020 Published by Elsevier Ltd.
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Access this article on ScienceDirectLinked Article
- A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practiceEuropean Journal of CancerVol. 113
- PreviewAdult guidelines recommend BEP (bleomycin, etoposide, cisplatin) for all ovarian germ cell tumours, causing debilitating toxicities in young patients who will survive long term. Paediatricians successfully reduce toxicities by using lower bleomycin doses and substituting carboplatin for cisplatin, while testicular and paediatric immature teratomas (ITs) are safely managed with surgery alone.
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- Response to: A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practiceEuropean Journal of CancerVol. 130
