Background: Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of immature, immunosuppressive
cells that play a role in cancer induction, progression and immune evasion. Two major
MDSC subsets exist: polymorphonuclear (PMN-MDSC) and monocytic MDSC (M-MDSC). Recent
studies indicated that the immune reconstitution after autologous hematopoietic stem
cell transplantation (ASCT) is associated with outcome. Since MDSC are immunosuppressive
cells, we hypothesize that they play a role in the immune reconstitution after ASCT.
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P02.08
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© 2018 Published by Elsevier Inc.
