Background: Ovarian cancer metastasis occurs by direct multifocal seeding in the peritoneum as
well as by migration through the lymphatic system. High grade ovarian carcinoma patients
present distant metastases. Significant risk factors for the development of those
are stage, grade, and lymph node involvement. An increase of the number of lymphatic
vessels is shown in ovarian tumor and these vessels seem implicated in tumor progression.
While the tropism of ovarian cancer cells for fat is well described, the potential
impact of a fatty microenvironment on the dissemination of metastasis via lymphatic
vessels has never been investigated. In this study, we examined the effect of omental
fat on lymphangiogenesis in ovarian carcinoma
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to European Journal of CancerAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Article info
Publication history
P02.04
Identification
Copyright
© 2018 Published by Elsevier Inc.
