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A new combination immunotherapy approach with anti-PD-L1 and HER2/neu loaded dendritic cell vaccine along with saponin adjuvant

      Background: HER2/neu overexpression is highly associated with increased risk of cancer with poor prognosis which is especially seen in breast cancer along with some other cancer types such as gastric and ovarian cancers. Although HER2/neu overexpression is well characterized in various cancer types, no effective therapy is yet found against it.
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