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The adjuvant effect of melanin is superior to Incomplete Freund adjuvant in a tumor subunit vaccine model

      Background: We recently reported that synthetic melanin bound to subunit vaccine antigens significantly enhances CD8+ T-cell responses in mice [1]. In an established tumor model, we compared this vaccine approach to the standard adjuvant formulation combining the Incomplete Freund Adjuvant (IFA) and a TLR9 agonist.
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