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The authors regret that in the previously published paper, there is an error in the bands for the first part of figure 2b. The first pair of bands is incorrect. They have reviewed the original blot and realised that the error occurred when producing the composite figure; originally, there were only 3 pairs of bands. To strengthen the data the authors thought it best to include 4 pairs of bands. It appears that this is where the error arose from subsequent scanning of the original blot film (back to front). The below figure 2b is now correct.
The authors would like to apologise for any inconvenience caused.
The aim of this study was to investigate the expression of Zonula Occludens (ZO) proteins ZO-1, ZO-2 and ZO-3, and MUPP-1 (multi-PDZ domain protein 1), peripheral/plaque proteins that function in maintaining tight junction integrity and in transducing regulatory signalling events in patients with primary breast cancer. Breast cancer primary tumours (n = 114) and background tissues (n = 30) were processed for quantitative-polymerase chain reaction (PCR) analysis, Western blotting and immunostaining. Standardised transcript levels of ZO-1 and MUPP-1 were significantly lower in patients with metastatic disease compared with those remaining disease-free (DF) (median follow-up 72.2 months).