Abstract
Gastric cancer incidence and mortality decreased substantially over the last decades
in most countries worldwide, with differences in the trends and distribution of the
main topographies across regions. To monitor recent mortality trends (1980–2011) and
to compute short-term predictions (2015) of gastric cancer mortality in selected countries
worldwide, we analysed mortality data provided by the World Health Organization. We
also analysed incidence of cardia and non-cardia cancers using data from Cancer Incidence
in Five Continents (2003–2007). The joinpoint regression over the most recent calendar
periods gave estimated annual percent changes (EAPC) around −3% for the European Union
(EU) and major European countries, as well as in Japan and Korea, and around −2% in
North America and major Latin American countries. In the United States of America
(USA), EU and other major countries worldwide, the EAPC, however, were lower than
in previous years. The predictions for 2015 show that a levelling off of rates is
expected in the USA and a few other countries. The relative contribution of cardia
and non-cardia gastric cancers to the overall number of cases varies widely, with
a generally higher proportion of cardia cancers in countries with lower gastric cancer
incidence and mortality rates (e.g. the USA, Canada and Denmark). Despite the favourable
mortality trends worldwide, in some countries the declines are becoming less marked.
There still is the need to control Helicobacter pylori infection and other risk factors, as well as to improve diagnosis and management,
to further reduce the burden of gastric cancer.
Keywords
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Article info
Publication history
Published online: March 19, 2014
Accepted:
January 30,
2014
Received in revised form:
January 27,
2014
Received:
December 19,
2013
Identification
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