Advertisement
Research Article| Volume 42, ISSUE 13, P2050-2063, September 2006

Non-Hodgkin’s lymphoma incidence and survival in European children and adolescents (1978–1997): Report from the Automated Childhood Cancer Information System project

DOI:https://doi.org/10.1016/j.ejca.2006.05.005
Non-Hodgkin’s lymphoma incidence and survival in European children and adolescents (1978–1997): Report from the Automated Childhood Cancer Information System project
Previous ArticleHodgkin’s disease incidence and survival in European children and adolescents (1978–1997): Report from the Automated Cancer Information System project
Next ArticleChildhood central nervous system tumours – incidence and survival in Europe (1978–1997): Report from Automated Childhood Cancer Information System project

      Abstract

      Non-Hodgkin’s lymphomas (NHLs) constitute a large and heterogeneous group of malignant tumours. This paper describes and interprets geographical patterns (1988–1997) and time trends (1978–1997) of NHL incidence and survival in European children and adolescents. All 7702 lymphomas that were not Hodgkin’s, were extracted from the Automated Childhood Cancer Information System (ACCIS) database and included in different analyses. In children under 15 years of age and for the period 1988–1997, the overall NHL age-adjusted incidence rate was 9.4 per million and has been increasing over 20 years by 0.9% per year on average (P = 0.002). In adolescents aged 15–19 years, the age-specific incidence rate was 15.9 per million, increasing annually by 1.7% (P = 0.007). Five-year survival of children diagnosed in 1988–1997 was 77%, ranging from 58% in the East to 83% in the West. A substantial increase in survival was observed in all European regions. Systematic monitoring and evaluation of childhood and adolescent data on NHL will contribute to further improvement in public health policy for the young population of Europe.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to European Journal of Cancer
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Register: Create an account
      Institutional Access: Sign in to ScienceDirect

      References

      1. Percy CL, Smith MA, Linet M, Gloeckler Ries LA, Friedman DL. Lymphomas and reticuloendothelial neoplasms. In: Ries LAG, Smith MA, Gurney JG, et al., editors. Cancer incidence and survival among children and adolescents: United States. SEER Program 1975–1995. National Cancer Institute, SEER Program. Bethesda, MD: NIH Pub. No. 99-4649; 1999, p. 35–50.

        View in Article

      2. Parkin DM, Kramárová E, Draper GJ, et al., editors. International incidence of childhood cancer: volume 2. IARC Scientific Publications No 144. Lyon: IARC; 1998.

        View in Article
        • Harris N.L.
        Mature B-cell neoplasms: introduction.
        in: Jaffe E.S. Harris N.L. Stein H. Vardiman J.W. Pathology and genetics. Tumours of haematopoietic and lymphoid tissues. World Health Organization Classification of Tumours. IARC Press, Lyon2001
        View in Article
        • Banks P.M.
        Changes in diagnosis of non-Hodgkin’s lymphomas over time.
        Cancer Research. 1992; 52: 5453s-5455s
        View in Article

      5. Non-Hodgkin’s lymphoma pathologic classification project. National Cancer Institute sponsored study of classification of non-Hodgkin’s lymphomas: Summary and description of a Working Formulation for clinical usage. Cancer 1982;49:2112-2135.

        View in Article
        • Stanfeld A.G.
        • Diebold J.
        • Kapanci Y.
        • et al.
        Updated Kiel classification for lymphomas.
        Lancet. 1988; i: 292-293
        View in Article
        • Harris N.L.
        • Jaffe E.S.
        • Stein H.
        • et al.
        A revised European-American Classification of Lymphoid Neoplasms: a proposal from the International Lymphoma Study Group.
        Blood. 1994; 84: 1361-1392
        View in Article
        • Gaidano G.
        • Dalla-Favera R.
        Lymphomas.
        in: De Vita Jr., V. Hellman S. Rosenberg S. Cancer. Principles & practice of oncology. Lippincott-Raven Publishers, Philadelphia1997: 2131-2145
        View in Article
        • Mueller N.E.
        • Evans A.S.
        • London W.T.
        Viruses.
        in: Schottenfeld D. Fraumeni Jr., J.F. Cancer epidemiology and prevention. Oxford University Press, New York, NY1996
        View in Article
        • Diebold J.
        • Jaffe E.
        • Raphael M.
        • Warnke R.A.
        Burkitt lymphoma.
        in: Jaffe E.S. Harris N.L. Stein H. Vardiman J.W. Pathology and genetics. Tumours of haematopoietic and lymphoid tissues. World Health Organization Clasification of Tumours. IARC Press, Lyon2001
        View in Article
        • Steliarova-Foucher E.
        • Stiller C.
        • Kaatsch P.
        • Coebergh J.-W.
        • Lacour B.
        • Parkin M.
        Geographical patterns and time trends of cancer incidence and survival among children and adolescents in Europe since the 1970s (the ACCIS project): an epidemiological study.
        Lancet. 2004; 364: 2097-2105
        View in Article
        • Kramárová E.
        • Stiller C.A.
        The International Classification of Childhood Cancer.
        Int J Cancer. 1996; 68: 759-765
        View in Article

      13. Jensen OM, Parkin DM, MacLennan R, Muir CS, Skeet R, editors. Cancer registration: principles and methods. IARC Scientific Publications No. 95. Lyon: IARC; 1991, p. 159–176.

        View in Article
        • Kalbfleisch J.D.
        • Prentice R.L.
        The statistical analysis of failure time data.
        John Wiley & Sons, New York1980
        View in Article
        • Peto R.
        • Pike M.C.
        • Armitage P.
        • et al.
        Design and analysis of randomized clinical trials requiring prolonged observation of each patient, II, analysis and examples.
        Br J Cancer. 1977; 35: 1-39
        View in Article

      16. Teppo L, Hakama M, Sankila R. Finnish Cancer Registry 1980–1989. In: Parkin DM, Kramárová E, Draper GJ, et al., editors. International incidence of childhood cancer: volume 2. IARC Scientific Publications No 144. Lyon: IARC; 1998, p. 261–263.

        View in Article

      17. Andersen A, Langmark F, Glattre E, Dahl T, Johansen A. Norwegian Cancer Registry, 1980–1989. In: Parkin DM, Kramárová E, Draper GJ, et al., editors. International incidence of childhood cancer: volume 2. IARC Scientific Publications No 144. Lyon: IARC; 1998, p. 261–3.

        View in Article
        • Gerard-Marchant R.
        • Hamlin I.
        • Lennert K.
        • Rilke F.
        • Stansfeld A.G.
        • van Unnik J.A.M.
        Classification of non-Hodgkin’s lymphoma.
        Lancet. 1947; II: 406-408
        View in Article
      19. Fritz A. Percy C. Jack A. International classification of diseases for oncology. 3rd edition. World Health Organization, Geneva2000
        View in Article
        • Brunning R.D.
        • Borowitz M.
        • Matutes E.
        • Head D.
        • Flandrin G.
        • Swerdlow S.H.
        • et al.
        Precursor B lymphoblastic leukaemia/lymphoblastic lymphoma. Precursor T lymphoblastic leukaemia/lymphoblastic lymphoma.
        in: Jaffe E.S. Harris N.L. Stein H. Vardiman J.W. Pathology and genetics. Tumours of haematopoietic and lymphoid tissues. World Health Organization Classification of Tumours. IARC Press, Lyon2001
        View in Article
        • Coebergh J.W.W.
        • van der Does-van der Berg A.
        • Kamps W.A.
        • Rammeloo J.A.
        • Valkenburg H.A.
        • van Wering E.R.
        Malignant lymphomas in children in the Netherlands in the period 1973–1985: incidence in relation to leukaemia.
        Med Ped Onc. 1991; 19: 169-174
        View in Article
        • Parkin D.M.
        • Stiller C.A.
        • Draper G.J.
        • Bieber C.A.
        The international incidence of childhood cancer.
        Int J Cancer. 1988; 42: 511-520
        View in Article
        • Bunin G.R.
        Nongenetic causes of childhood cancers: evidence from international variation, time trends, and risk factor studies.
        Toxicol Appl Pharmacol. 2004; 199: 91-103
        View in Article
        • Groves F.D.
        • Linet M.S.
        • Travis L.B.
        • Devesa S.S.
        Cancer Surveillance Series: non-Hodgkin’s lymphoma incidence by histologic subtype in the United States from 1978 through 1995.
        J Natl Cancer Inst. 2000; 92: 1240-1251
        View in Article
        • Gatta G.
        • Corazziari I.
        • Magnani C.
        • Peris-Bonet R.
        • Roazzi P.
        • Stiller C.
        Childhood cancer survival in Europe.
        Ann Oncol. 2003; 14: v119-v127
        View in Article
        • Lones M.A.
        • Perkins S.L.
        • Sposto R.
        • et al.
        Non-Hodgkin’s lymphoma arising in bone in children and adolescents is associated with an excellent outcome: a Children’s Cancer Group report.
        J Clin Oncol. 2002; 20: 2293-2301
        View in Article
        • Gatta G.
        • Capocaccia R.
        • Coleman M.P.
        • Gloeckler L.A.
        • Berrino F.
        Childhood cancer survival in Europe and the United States.
        Ann Oncol. 2003; 14: v119-v127
        View in Article
        • Micheli A.
        • Coebergh J.W.
        • Mugno E.
        • Massimiliani E.
        • Sant M.
        • Oberaigner W.
        • et al.
        European health systems and cancer care.
        Ann Oncol. 2003; 14: v42-v60
        View in Article
        • Sandlund J.T.
        • Downing J.R.
        • Crist W.M.
        Non-Hodgkin’s lymphoma in childhood.
        N Engl J Med. 1996; 334: 1238
        View in Article
        • Stiller C.A.
        • Parkin D.M.
        International variations in the incidence of childhood lymphomas.
        Pediatr Perinat Epidemiol. 1990; 4: 303-324
        View in Article
        • Peris-Bonet R.
        • Abad F.
        • Melchor I.
        • Guallar E.
        • Garcia A.
        Childhood cancer incidence registration in the province of Valencia, Spain 1983–90.
        J Epidem Biostatistics. 1996; 1: 107-113
        View in Article
        • Gatta G.
        • Capocaccia R.
        • De Angelis R.
        • Stiller C.
        • Coebergh J.W.
        Cancer survival in European adolescents and young adults.
        Eur J Cancer. 2003; 39: 2600-2610
        View in Article

      33. Hölzer S, Stewart A, Dudeck J. Assessing patterns of care. In: Sankila R, Black R, Coebergh JW, Démaret E, Forman D, Gatta G, Parkin DM, editors. Evaluation of clinical care by cancer registries. IARC Technical Publication No. 37. Lyon: IARC Press; 2003.

        View in Article

      Article info

      Identification

      DOI: https://doi.org/10.1016/j.ejca.2006.05.005

      Copyright

      © 2006 Published by Elsevier Inc.

      ScienceDirect

      Access this article on ScienceDirect
      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the for this site.
      Copyright © 2023 Elsevier Inc. except certain content provided by third parties. The content on this site is intended for healthcare professionals.


      RELX