Abstract
We conducted a retrospective seroepidemiological study to evaluate the relationship
between past chlamydial infection and primary fallopian tube carcinoma (PFTC). Postoperative
serum samples were drawn from 79 consecutive patients treated for PFTC in 1985–2000.
For each case two controls were selected. Serum samples were analysed for IgG antibodies
to different C. trachomatis serotype pools and to C. pneumoniae. Seropositivity in general or serum antibody levels to different C. trachomatis serovars or C. pneumoniae did not differ between PFTC patients and controls. The lack of association between
anti-chlamydial antibodies and PFTC suggests that past chlamydial infection does not
play a role in the etiopathogenesis of PFTC. However, because chlamydial infection
is common at young age and PFTC develops decades later, we cannot definitively exclude
the possibility that C.trachomatis contributes to the development of PFTC.
Keywords
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Article info
Publication history
Accepted:
November 29,
2005
Received:
November 24,
2005
Identification
Copyright
© 2006 Elsevier Ltd. Published by Elsevier Inc. All rights reserved.
