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Review| Volume 40, ISSUE 14, P2033-2040, September 2004

The treatment of cancer in Greek antiquity

      Abstract

      Literary sources provide considerable information on the existence of various malignant tumours in the classical period. Based on a close reading of the ancient Greek medical treatises, this paper traces the history of the treatment of cancer by examining the theories of tumour formation, as they were codified by leading physicians of antiquity, together with the therapeutic methods they proposed in their writings. The discussion focuses on a series of medical texts beginning with the Hippocratic corpus (ca. 460–370 B.C.) and the voluminous works of Galen (129–199 A.D.) and extends to medical handbooks (Oreibasios, Aetios of Amida, Paul of Aegina) composed in subsequent centuries up to the end of the ancient world (VII c. A.D.).

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      References

        • Lloyd G.E.R.
        The hippocratic question.
        The Classical Quarterly. 1975; 25: 171-192
      1. É. Littré, editor. Hippocrates, Prorrheticon II.11. Opera omnia, vol. IX, Paris, 1861, 30–32

      2. Hippocrates, Coa praesagia. Opera omnia, vol. V, Paris, 1846, 502

      3. Hippocrates, Aphorismi VI. 38. Opera omnia, vol. IV, Paris, 1822, 572

        • Retief F.P.
        • Ciliers L.
        Tumours and cancers in Graeco-Roman times.
        SAMJ. 2001; 91: 171-348
      4. Hippocrates, De morbis popularibus, VII.1.111 and 116, Opera omnia, vol. V, Paris, 1823, 460–462

        • Grmek M.D.
        Diseases in the Ancient Greek World [transl. by M. and L. Muellner].
        The John Hopkins University Press, Baltimore, London1989 (p. 350)
      5. Hippocrates, De morbis popularibus, II. 6. 22. Opera omnia, vol. V, Paris, 1823, 136

        • Retsas S.
        On the antiquity of cancer: from hippocrates to Galen.
        in: Retsas S. Palaeo-oncology: the antiquity of cancer. Farrand Press, London1986: 41-53
      6. Hippocrates, De mulierum affectibus II. 133. 2. Opera omnia, vol. VIII, Paris, 1824, p. 280–284. De natura muliebri 31.3-6, vol. VII, Paris, 1824, 346

      7. Kouzes, A. Cancer in ancient Greek physicians, Athens, 1902 [in Greek]

      8. Soranos d' Éphèse. In Burguiere P, Gourevitch D, Malinas Y, eds. Maladies des femmes, vol. II, 2; IV, Les Belles Lettres, Paris, 1990/2000, XXVII

      9. Pedanius Dioscurides. In Wellmann M, ed. De materia medica, vol. I, Nr. 104, 178,1–16; Nr. 166, 231,1–233,9; vol. II, Nr. 93–94, 251,7–253,9, Berlin, 1958

      10. Pedanius Dioscurides. In Wellmann M, editor, Euporista, vol. III, Nr. 72, 281,6; De materia medica, vol. I, Nr. 68, 61–65; Nr. 158, 223,1–224,11, Berlin, 1958

      11. Pedanius Dioscurides. De materia medica, vol. I, Nr. 10,125,15–19, Berlin, 1958

      12. Alexander of Aphrodisias, Problematum Sectio I. In Ideler IL, ed. Physici et medici Greci minores, Leipzig, 1841, 32,4–19; 34,21–29. On the incurable round ulcers, see also Cassii Felicis, Problemata, in Physici et medici Greci minores, I, op. cit., 144–146

      13. Mauroudes A. Archigenes Philippou Apameus [Ponemata – 3], 42, n. 181, 140, 316–318, Athens, 2000 [in Greek]

      14. Aetios of Amida. In Zervos S, ed. Sermo sextidecimus et ultimus. Erstens aus Handschriften veröffentlicht, XVI, Leipzig, 1901, 42–43, 60–61

      15. Aetios of Amida, Zervos, op. cit., XVI, 48, 66. Paul of Aegina. In Heiberg IL, ed. Epitomae medicae libri septem [CMG IX1], IV, Leipzig, 1921, 26,4, 349,14–17

      16. Aetios of Amida, Zervos, op. cit., XVI, 42, 60–61

      17. Aetios of Amida, Zervos, op. cit., XVI, 45, 48, 62–63, 66–67

      18. Hankinson RJ. Galen on the therapeutic method. Books I and II. Oxford, Clarendon Press, 1991, 42–43, 164–165

      19. Galen. In Kühn CG, ed. Opera omnia, vol. XI, II, 12, 139–141, Leipzig, 1826; cf. vol. X, V, Leipzig, 1825, 9, 972–975

      20. Galen. Opera omnia, Kühn, op. cit., vol. XI, II, 12, 142–143

      21. Galen. Opera omnia, Kühn, op. cit., vol. XI, II, 12, 139–143. For rendering into English the Greek medical terms, we used the work of Durling, RJ. A Dictionary of Medical terms in Galen [Studies in Ancient Medicine – 5], Leiden EJ Brill, 1993; and his Lexicographical notes on Galen's Pharmacological Writings, Glotta, vol. 57, 1979, 218–224

      22. Galen. Opera omnia, Kühn, vol. XII, I, 25, 234–235, Leipzig, 1826; vol. XII, I, 23, 230–233

      23. Galen. Opera omnia, Kühn, op. cit., vol. XII, I, 24–25, 343–345; vol. XII, I, 26, 345–347; vol. XII, I, 32–34, 353–359; vol. XII, I, 12, 377

      24. Galen. Opera omnia, Kühn, vol. XIII, IV, 11, 733–735, Leipzig, 1827

      25. Oreibasios. In: Raeder I, editor, Synopsis ad Eustathium, VII, 13, 219–220; vol. III, 35, 77–79, Leipzig-Berlin, 1926

      26. Körbler J. Einige Beiträge zur Geschichte der Krebskrankheit in Byzanz, Janus 1971, 58, 101–105. Id. Geschichte der Krebskrankheit: Schiksale der Kranken, der Ärzte und der Forscher, Zagreb, 1973, 19

      27. Oreibasios. Synopsis ad Eustathium, op. cit., VII, 2, 212–213. VII, 4, 214. VII, 11, 217. III, 35, 77–79

      28. Oreibasios. In Raeder I, ed. Collectionum medicarum reliquiae, vol. I, XV, 3, 296–297, Leipzig-Berlin, 1928

      29. Oreibasios. Synopsis ad Eustathium, op. cit., VII, 11, 217–218. Collectionum medicarum reliquiae, op. cit., IV, 136, 299, 5-300, 9. XV, 3, 299–300

      30. Alexander von Tralles. In Puschmann Th, ed. Original-Text und Übersetzung nebst einer einleitende Abhandlung. Ein Beitrag zur Geschichte der Medicin, vol. II, Wien 1879, 221

      31. Aetios of Amida. Sermo sextidecimus. Zervos, op. cit., XVI, 47, 65–66

      32. Aetios of Amida, op. cit., XVI, 96, 143–144

      33. Paul of Aegina, Epitomae medicae, Heiberg, III, 67, IV, 26, 284–285, 348–349, Aetios of Amida, Sextidecimus, Zervos, op. cit., XVI, 94, 141–142; XIV, 57. Oreibasios, Synopsis ad Eustathium, Raeder, op. cit., VII, 13, 219–220

      34. Gregory of Nyssa, Contra Eunomium. In Jaeger W, ed. Gregorii Nysseni opera, II, III.5.8., 174, 7–9, Leiden, 1960

      35. John Chrysostom, Ad Stagirium. In Migne J-P, ed. Patrologia Graeca, vol. 47, Paris, 1857, 490

        • Fitton J.
        The death of Theodora.
        Byzantion. 1976; 46: 119
      36. Michael Psellus. In Westerink LG, ed. Poemata, IX, Stuttgart 1992, 1193–1200, 1304–1309, Aetios of Amida, Sermo sextidecimus, Zervos, op. cit., XVI, 96,143, 5ff; Paul of Aegina, Epitomae medicae, Heiberg, op. cit., IV, 26, 348, 6–14

      37. Ioannes Actuarius, De Diagnosi lib. II. In Ideler IL, ed. Physici et medici graeci minores, vol. II, Leipzig, 1842, XXXVII–XXXVII, 460, 18–462, 2, Paul of Aegina, Epitomae medicae, Heiberg, op. cit., IV, 26, 348, 5–21; IV, 30,1–13; III, 68, l. 1ff

      38. Pedanius Dioscurides. De materia medica, Wellmann, op. cit., vol. II, Nr. 4, 8, 7–8, app. crit. line 10. vol. I, Nr. 151, 217, app. crit. line 7; Nr. 170, 237, app. crit. line 14. See also Riddle, JM, Byzantine Commentaries on Dioscorides, Dumbarton Oaks Papers 1984, 38, 99–100