Abstract
Trends in death certification rates from all cancers and seven selected cancer sites
(bone sarcoma, soft-tissue sarcoma, ovary, testis, non-Hodgkin's lymphomas, Hodgkin's
disease, leukaemias) were analysed for the population aged 15–24 years in Europe and,
for comparative purposes, in the United States of America (USA) and Japan over the
period of 1965–1998. Overall, there was a decrease in total cancer mortality of approximately
40% for both sexes. The declined mortality is largely attributable to better treatments
and inclusion in multicentre clinical trials. The degree of improvement was similar
in Japan and the USA, but was less in Eastern European countries, reflecting delays
in the application of effective treatments, and limited involvement in large, well-designed
clinical trials for these curable cancers in Eastern Europe.
Keywords
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Article info
Publication history
Accepted:
March 27,
2003
Received in revised form:
February 27,
2003
Received:
November 6,
2002
Identification
Copyright
© 2003 Elsevier Science Ltd. Published by Elsevier Inc. All rights reserved.